deep Transcranial Magnetic Stimulation (Deep TMS) using Brainsway’s H-coils is a novel development in non-invasive neuromodulation. The unique ability to stimulate deeper neuronal structures than any other commercially available TMS system may seem almost mythical; but Deep TMS is a reality, born of ingenuity, science and engineering.
Transcranial magnetic stimulation (TMS) is delivered using an electromagnetic coil placed against the scalp surface. The coil generates a brief but powerful magnetic field pulses, which pass unimpeded through the scalp and skull and induce an electric field in the brain.
The randomized double-blind sham-controlled multicenter trial leading to FDA clearance of the BrainsWay TMS device was conducted globally at 20 sites in the U.S., Israel, Germany and Canada.
The study included 212 medication-free patients with major depressive disorder who had not received benefit from 1 to 4 antidepressant trials (mean=1.70). Patients were randomly assigned to monotherapy with either active Deep TMS with the H1-coil or sham TMS for a 4-week acute treatment phase followed by a 12-week maintenance phase of bi-weekly treatment.
This clearly shows the superiority of dTMS by week 3, which continued as treatment progressed.